We can use focus to guide the audience's attention and create depth in an otherwise 2-dimensional image.
Many cameras have a very helpful automatic over-ride button which will temporarily let the camera find the focus and lock it there when it is released back into manual mode.
If the camera is left on auto-focus it may annoy your audience as it randomly searches to focus first on the foreground then background. This often happens when someone walks across a shot
Keep it out of focus - I want to win the foreign picture award - Billy Wilder
Focussing in High definition is more difficult because the tolerances of the higher resolution are lower; and what you might not see when filming could be very noticable when you finally view your work.
Simplified massively, depth of field is how much extra stays in focus in front of and behind what you have actually focused.
deep depth of field
shallow depth of field
Normally you want the biggest, deepest depth of field because:
A very cinematic technique that makes everything in front of and behind your subject ‘soft’, isolating them in the frame and removing any distractions from the performance.
Depth of field is a function of aperture (sometimes known as iris) in relation to image size (controlled by the lens's focal length, cameras chip size and how far away your charater is from the camera (subject distance).